Cells of the zona fasciculata and zona reticularis lack aldosterone synthase (CYP11B2) that converts corticosterone to aldosterone, and thus these tissues produce only the weak mineralocorticoid corticosterone. However, both these zones do contain the CYP17A1 missing in zona glomerulosa and thus produce the major glucocorticoid, cortisol. Zona fasciculata and zona reticularis cells also contain CYP17A1, whose 17,20-lyase activity is responsible for producing the androgens, dehydroepiandosterone (DHEA) and androstenedione. Thus, fasciculata and reticularis cells can make corticosteroids and the adrenal androgens, but not aldosterone.
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If you want to know how to inject steroids , the first thing you need to know is how to prepare for the injection. You know you need to stick it into the muscle tissue, and we’ll go into the specifics of that later on, but there’s more to it than that. There are eight specific steps you need to follow when injecting anabolic steroids, and while that may sound like a lot the whole process shouldn’t take but a minute. Failure to follow these eight remarkably simple steps can result in complications such as infections or simply very uncomfortable injections, and an unnecessarily sore injected area.