Saponins from the Gypsophila paniculata (baby’s breath) plant have been shown to significantly augment the cytotoxicity of immunotoxins and other targeted toxins directed against human cancer cells. The research groups of Professor Hendrik Fuchs ( Charité University, Berlin, Germany) and Dr David Flavell (Southampton General Hospital, United Kingdom) are working together toward the development of Gypsophila saponins for use in combination with immunotoxins or other targeted toxins for patients with leukaemia , lymphoma and other cancers .
NSAIDs may also elevate blood pressure and cause heart failure. The risk of heart attack and stroke achieved special notoriety with rofecoxib (Vioxx), a type of NSAID called a COX-2 inhibitor. It caused as many as 140,000 heart attacks in the . during the five years it was on the market (Vioxx was removed from the market in 2004). The regrettable experience with Vioxx raised awareness about the cardiovascular risk of NSAIDs, and led to further studies showing that the risk is not limited to Vioxx but is associated with all NSAIDs.